News

NIDCR Grants Funding to Unravel the Mysteries of Tooth Enamel Formation and Mineralization

By Dr. Den Besten on October 31, 2023
Enamel, a highly mineralized tissue, possesses a unique formation process unparalleled among all mineralized tissues, serving as the primary protective layer for dental structures. Its pertinence to oral health is underscored by the effects of mineralization defects, evident in conditions like...

Amelogenin Gene's miRNA: A New Hope for Bone Growth Regulation

By Dr. Yukiko Nakano on October 31, 2023
In a recent study, Nakano and coworkers explored the role of the amelogenin gene, which produces the amelogenin protein crucial for enamel formation. Our findings revealed that miR-exon4, a miRNA originating from exon4 of the amelogenin gene, targets the transcription factor nuclear factor I/A (NFI...

Dental Decay is Linked to Blood Infections in Children Receiving Stem Cell Transplants

By Dr. Den Besten on October 31, 2023
Hematopoietic cell transplantation (HCT) offers a potential cure for various pediatric diseases, but complications like blood stream infections (BSI) pose significant risks. There's emerging evidence linking the oral microbiome, specifically bacteria such as S. mitis, to the onset of BSI.  In a...