 
Professor
          D_OFS
      
            
      Associated Programs
DDS-PhD
PhD in Oral and Craniofacial Sciences
Center for Children's Oral Health Research
https://cor.ucsf.edu
Publications
Fluoride-related changes in the fetal cord blood proteome; a pilot study.
Environmental health : a global access science source
      
            
      
      Fluoride exposure and blood cell markers of inflammation in children and adolescents in the United States: NHANES, 2013-2016.
Environmental health : a global access science source
      
            
      
      WDR72 regulates vesicle trafficking in ameloblasts.
Scientific reports
      
            
      
      Three-Dimensional Culture of Ameloblast-Originated HAT-7 Cells for Functional Modeling of Defective Tooth Enamel Formation.
Frontiers in pharmacology
      
            
      
      TRPM7-Mediated Calcium Transport in HAT-7 Ameloblasts.
International journal of molecular sciences
      
            
      
      Maternal and fetal exposures to fluoride during mid-gestation among pregnant women in northern California.
Environmental health : a global access science source
      
            
      
      Fluoride related changes in behavioral outcomes may relate to increased serotonin.
Physiology & behavior
      
            
      
      The Importance of Connexin 43 in Enamel Development and Mineralization.
Frontiers in physiology
      
            
      
      Oral Sciences PhD Program Enrollment, Graduates, and Placement: 1994 to 2016.
Journal of dental research
      
            
      
      No Change in Bicarbonate Transport but Tight-Junction Formation Is Delayed by Fluoride in a Novel Ameloblast Model.
Frontiers in physiology
      
            
      
      Meeting report: a hard look at the state of enamel research.
International journal of oral science
      
            
      
      The Role of Na:K:2Cl Cotransporter 1 (NKCC1/SLC12A2) in Dental Epithelium during Enamel Formation in Mice.
Frontiers in physiology
      
            
      
      Corrigendum to " Mineralization-defects are comparable in fluorotic impacted human teeth and fluorotic mouse incisors" [Archives of Oral Biology 29 (July (83)) (2017) 214-221].
Archives of oral biology
      
            
      
      Importance of bicarbonate transport in pH control during amelogenesis - need for functional studies.
Oral diseases
      
            
      
      Mineralization-defects are comparable in fluorotic impacted human teeth and fluorotic mouse incisors.
Archives of oral biology
      
            
      
      Mediator 1 contributes to enamel mineralization as a coactivator for Notch1 signaling and stimulates transcription of the alkaline phosphatase gene.
The Journal of biological chemistry
      
            
      
      Buffering of protons released by mineral formation during amelogenesis in mice.
European journal of oral sciences
      
            
      
      The C-terminus of amelogenin enhances osteogenic differentiation of human cementoblast lineage cells.
Journal of periodontal research
      
            
      
      Effects of C-Terminal Amelogenin Peptide on Proliferation of Human Cementoblast Lineage Cells.
Journal of periodontology
      
            
      
      Ameloblast Modulation and Transport of Cl⁻, Na⁺, and K⁺ during Amelogenesis.
Journal of dental research
      
            
      
      Slc26a3/Dra and Slc26a6 in Murine Ameloblasts.
Journal of dental research
      
            
      
      Exon4 amelogenin transcripts in enamel biomineralization.
Journal of dental research
      
            
      
      Composition of mineralizing incisor enamel in cystic fibrosis transmembrane conductance regulator-deficient mice.
European journal of oral sciences
      
            
      
      Amelogenins as potential buffers during secretory-stage amelogenesis.
Journal of dental research
      
            
      
      Distinctive genetic activity pattern of the human dental pulp between deciduous and permanent teeth.
PloS one
      
            
      
      NBCe1 (SLC4A4) a potential pH regulator in enamel organ cells during enamel development in the mouse.
Cell and tissue research
      
            
      
      WDR72 models of structure and function: a stage-specific regulator of enamel mineralization.
Matrix biology : journal of the International Society for Matrix Biology
      
            
      
      Barrier formation: potential molecular mechanism of enamel fluorosis.
Journal of dental research
      
            
      
      Inductive ability of human developing and differentiated dental mesenchyme.
Cells, tissues, organs
      
            
      
      Leucine rich amelogenin peptide alters ameloblast differentiation in vivo.
Matrix biology : journal of the International Society for Matrix Biology
      
            
      
      The similarity between human embryonic stem cell-derived epithelial cells and ameloblast-lineage cells.
International journal of oral science
      
            
      
      Clinical efficacy and effects of xylitol wipes on bacterial virulence.
Advances in dental research
      
            
      
      Enamel pits in hamster molars, formed by a single high fluoride dose, are associated with a perturbation of transitional stage ameloblasts.
Caries research
      
            
      
      Effects of xylitol wipes on cariogenic bacteria and caries in young children.
Journal of dental research
      
            
      
      Amelogenin exons 8 and 9 encoded peptide enhances leucine rich amelogenin peptide mediated dental pulp repair.
Cells, tissues, organs
      
            
      
      Developmental expression of solute carrier family 26A member 4 (SLC26A4/pendrin) during amelogenesis in developing rodent teeth.
European journal of oral sciences
      
            
      
      Fluoride incorporation into apatite crystals delays amelogenin hydrolysis.
European journal of oral sciences
      
            
      
      Evolutionary story of mammalian-specific amelogenin exons 4, "4b", 8, and 9.
Journal of dental research
      
            
      
      Chronic fluoride toxicity: dental fluorosis.
Monographs in oral science
      
            
      
      Altered self-assembly and apatite binding of amelogenin induced by N-terminal proline mutation.
Archives of oral biology
      
            
      
      NBCe1 in mouse and human ameloblasts may be indirectly regulated by fluoride.
Journal of dental research
      
            
      
      Fate of fluoride-induced subameloblastic cysts in developing hamster molar tooth germs.
Archives of oral biology
      
            
      
      Ameloblast differentiation in the human developing tooth: effects of extracellular matrices.
Matrix biology : journal of the International Society for Matrix Biology
      
            
      
      Horizontal transmission of mutans streptococci in children.
Journal of dental research
      
            
      
      The impact of fluoride on ameloblasts and the mechanisms of enamel fluorosis.
Journal of dental research
      
            
      
      Calcium-mediated differentiation of ameloblast lineage cells in vitro.
Journal of experimental zoology. Part B, Molecular and developmental evolution
      
            
      
      Dentin extracellular matrix molecules implanted into exposed pulps generate reparative dentin: a novel strategy in regenerative dentistry.
Journal of dental research
      
            
      
      Functional roles of prolines at amelogenin C terminal during tooth enamel formation.
Cells, tissues, organs
      
            
      
      The effect of fluoride on enamel and dentin formation in the uremic rat incisor.
Pediatric nephrology (Berlin, Germany)
      
            
      
      Inflammatory and immunological aspects of dental pulp repair.
Pharmacological research
      
            
      
      Reduced amelogenin-MMP20 interactions in amelogenesis imperfecta.
Journal of dental research
      
            
      
      Comparative properties of recombinant human and bovine matrix metalloproteinase-20.
Archives of oral biology
      
            
      
      Effects of fluoride on the interactions between amelogenin and apatite crystals.
Journal of dental research
      
            
      
      Matricellular molecules and odontoblast progenitors as tools for dentin repair and regeneration.
Clinical oral investigations
      
            
      
      The effect of LRAP on enamel organ epithelial cell differentiation.
Journal of dental research
      
            
      
      Dentonin, a MEPE fragment, initiates pulp-healing response to injury.
Journal of dental research
      
            
      
      JNK/c-Jun signaling pathway mediates the fluoride-induced down-regulation of MMP-20 in vitro.
Matrix biology : journal of the International Society for Matrix Biology
      
            
      
      Micromolar fluoride alters ameloblast lineage cells in vitro.
Journal of dental research
      
            
      
      Elevated TGF-beta2 signaling in dentin results in sex related enamel defects.
Archives of oral biology
      
            
      
      Comparative calcium binding of leucine-rich amelogenin peptide and full-length amelogenin.
European journal of oral sciences
      
            
      
      Differentiation of human ameloblast-lineage cells in vitro.
European journal of oral sciences
      
            
      
      Fluoride down-regulates the expression of matrix metalloproteinase-20 in human fetal tooth ameloblast-lineage cells in vitro.
European journal of oral sciences
      
            
      
      Growth of ameloblast-lineage cells in a three-dimensional Matrigel environment.
European journal of oral sciences
      
            
      
      Self-assembly and effect on crystal growth of the leucine-rich amelogenin peptide.
European journal of oral sciences
      
            
      
      The impact of bioactive molecules to stimulate tooth repair and regeneration as part of restorative dentistry.
Dental clinics of North America
      
            
      
      On-column activation of bovine recombinant metalloproteinase 20.
Analytical biochemistry
      
            
      
      Amelogenin control over apatite crystal growth is affected by the pH and degree of ionic saturation.
Orthodontics & craniofacial research
      
            
      
      Mouse amelogenin exons 8 and 9: sequence analysis and protein distribution.
Journal of dental research
      
            
      
      MEPE is downregulated as dental pulp stem cells differentiate.
Archives of oral biology
      
            
      
      Characterization of human primary enamel organ epithelial cells in vitro.
Archives of oral biology
      
            
      
      Effects of sodium fluoride on the actin cytoskeleton of murine ameloblasts.
Archives of oral biology
      
            
      
      Amelogenin-guided crystal growth on fluoroapatite glass-ceramics.
Journal of dental research
      
            
      
      Dentonin, a fragment of MEPE, enhanced dental pulp stem cell proliferation.
Journal of dental research
      
            
      
      X-linked amelogenesis imperfecta may result from decreased formation of tyrosine rich amelogenin peptide (TRAP).
Archives of oral biology
      
            
      
      Early childhood caries: an overview with reference to our experience in California.
Journal of the California Dental Association
      
            
      
      Effects of fluoride on rat dental enamel matrix proteinases.
Archives of oral biology
      
            
      
      Expression of alternatively spliced RNA transcripts of amelogenin gene exons 8 and 9 and its end products in the rat incisor.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
      
            
      
      Stem cell properties of human dental pulp stem cells.
Journal of dental research
      
            
      
      Identification of the calcium-sensing receptor in the developing tooth organ.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
      
            
      
      The effect of TGF-beta 2 on dentin apposition and hardness in transgenic mice.
Advances in dental research
      
            
      
      Reduced hydrolysis of amelogenin may result in X-linked amelogenesis imperfecta.
Matrix biology : journal of the International Society for Matrix Biology
      
            
      
      Increased fluoride content in the femur growth plate and cortical bone of uremic rats.
Pediatric nephrology (Berlin, Germany)
      
            
      
      Is teething associated with diarrhea?
The Western journal of medicine
      
            
      
      Activation of recombinant bovine matrix metalloproteinase-20 and its hydrolysis of two amelogenin oligopeptides.
European journal of oral sciences
      
            
      
      Development and characterization of an SV40 immortalized porcine ameloblast-like cell line.
European journal of oral sciences
      
            
      
      Biological mechanisms of dental fluorosis relevant to the use of fluoride supplements.
Community dentistry and oral epidemiology
      
            
      
      Canadian Consensus Conference on the appropriate use of fluoride supplements for the prevention of dental caries in children.
Journal (Canadian Dental Association)
      
            
      
      Identification of two additional exons at the 3' end of the amelogenin gene.
Archives of oral biology
      
            
      
      Fluoride levels in whole saliva of preschool children after brushing with 0.25 g (pea-sized) as compared to 1.0 g (full-brush) of a fluoride dentifrice.
Pediatric dentistry
      
            
      
      Alternative splicing of amelogenin mRNA from rat incisor ameloblasts.
Journal of dental research
      
            
      
      Purification of nonamelogenin proteins from bovine secretory enamel.
Calcified tissue international
      
            
      
      Neurotoxicity of sodium fluoride in rats.
Neurotoxicology and teratology
      
            
      
      Effects of chronic fluoride exposure on morphometric parameters defining the stages of amelogenesis and ameloblast modulation in rat incisors.
The Anatomical record
      
            
      
      Expression of bone protein mRNA at physiological fluoride concentrations in rat osteoblast culture.
Bone and mineral
      
            
      
      Characterization of amelogenin mRNA from secretory- and maturation-stage rat incisor enamel.
Archives of oral biology
      
            
      
      Biological mechanisms of fluorosis and level and timing of systemic exposure to fluoride with respect to fluorosis.
Journal of dental research
      
            
      
      Fluoride binding by matrix proteins in rat mineralizing tissue.
Archives of oral biology
      
            
      
      The presence and possible functions of the matrix metalloproteinase collagenase activator protein in developing enamel matrix.
The Biochemical journal
      
            
      
      Enamel proteases in secretory and maturation enamel of rats ingesting 0 and 100 PPM fluoride in drinking water.
Advances in dental research
      
            
      
      Separation by polyacrylamide gel electrophoresis of multiple proteases in rat and bovine enamel.
Archives of oral biology
      
            
      
      Studies on the changes in developing enamel caused by ingestion of high levels of fluoride in the rat.
Advances in dental research
      
            
      
      Changes in the fluoride-induced modulation of maturation stage ameloblasts of rats.
Journal of dental research
      
            
      
      Oral self-mutilation in a child with congenital toxoplasmosis: a clinical report.
Pediatric dentistry
      
            
      
      The effects of chronic high fluoride levels on forming enamel in the rat.
Archives of oral biology